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The presence of VATCs was associated with a higher risk of vancomycin-associated nephrotoxicity, and patients with VATCs had a longer length of hospital stay and a higher mortality rate

Furthermore, the trajectory of the weight loss curves suggested that at 48 weeks the plateau of weight was not yet reached and all the participants in the 8 and 12 mg had a weight reduction of 5% or more, which is currently the minimum threshold for efficacy [64]