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Astroglial NMDA receptors inhibit expression of K4.1 channels in glutamate-overexposed astrocytes in vitro and in the brain of rats with acute liver failure

As for body composition or weight changes, there are peptides that are proven to help many people reduce weight: GLP-1s

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I filed a patent to use GLP-1 as an anxiolytic, but really, the mice were just sick patft.uspto.gov/netacgi/nph-Pa The CNS GLP-1 food intake #weightloss #obesity story has turned out to be far more scientifically interesting and clinically relevant than I first appreciated

Moeller LC, Cao X, Dumitrescu AM, Seo H, Refetoff S