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Such mutations impair cellular uptake of riboflavin, leading to reduced FMN and FAD synthesis and consequent dysfunction of mitochondrial FAD-dependent enzymes, culminating in axonal degeneration, motor neuron disease, and sensory neuropathy

Minimizes Free Radical Damage Glutathione is a powerful antioxidant that neutralizes free radicals and protects the skin from environmental damage

Using CRISPR/Cas9 we then disrupted the CSE genomic locus (Figure S2B)

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As interest in the therapeutic potential of DSIP grows, studies continue to explore its applications in treating sleep disorders, chronic pain conditions, and other neurological issues, making it a valuable focus in the field of neurobiology and sleep medicine