445 Interestingly, the mRNA expression levels of CREB, PGC-1, NRF-1, NRF-2, and TFAM are decreased as early as 1 month of age when there is no significant A oligomer deposition in 3xTg-AD mouse (harboring PS1, APP, and tau human transgenes)
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doi: 10.1089/neu.2009.0987
Severity of anxiety- but not depression- is associated with oxidative stress in major depressive disorder
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