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The study participants were hypertensive (clinic systolic/diastolic BP of 140-179/90-109 mmHg and 24-hour ambulatory systolic/diastolic BP 130/80 mmHg) patients enrolled in a randomized controlled trial and treated with amlodipine 510 mg or nifedipine gastrointestinal therapeutic system (GITS) 3060 mg once daily

That single-molecule design is what separates it from stacking three drugs: the pharmacokinetics are unified, and the once-weekly half-life comes from a fatty-acid modification similar to the one used on semaglutide and tirzepatide

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Can I request a higher dose than 2.4 mg