3,4 In addition to their antitumour effects, ICIs have been reported to cause characteristic adverse events, called immune-related adverse events (irAEs), 5 in the lung, skin, gastrointestinal tract, liver and endocrine glands
Additionally, treatment with GLP-1RA and exendin-4 increased the expression of the calcitonin gene in the thyroids of normal (wild-type) mice
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Studies in adults also indicate the peptides safety, primarily reporting injection site reactions such as [14, 15]: Pain Swelling Inflammation Induration Bleeding A 16-week sermorelin study also observed temporary hyperlipidemia in some participants, possibly due to increased fat release from adipose cells [17]