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doi: 10.3389/fmed.2024.1323091 31 LiF.WenX.XueP.XuH.WuP.XuZ.et al

In addition, at later stages of pluripotency, -KG derived from glutamine can promote early differentiation, suggesting that the stage of cellular maturity can alter the effect of -KG 105

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Recent studies using both in vitro and in vivo models indicate that glycyrrhizin directly targets and binds to the RNA-binding protein CUG-binding protein 1(CUGBP1), activating the Interferon (IFN)-/Signal Transducer and Activator of Transcription (STAT)1/Smad7 signaling pathway and thereby inhibiting HSC activation, ultimately exerting anti-fibrotic effects (Wu et al., 2016)

Route of administration: IM, IV or SC as directed by veterinarian