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Exposure of cells of the Co-hyperaccumulator Crotalaria cobalticola and non-accumulators Raufolia serpentina , and Silene cucubalus to Co-ions resulted in an increase of citrate, indicating the involvement OA in the complexation of metal ions (Oven et al., 2002)

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253 In senescent cells, mitochondrial proton leak was observed, associated with the weakened proton gradient and further reducing the efficiency of ATP synthesis