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Although there have been some advances in the treatment of sepsis, mainly focused on broad-spectrum antibiotics, mortality rates remain high, urging for the search of new therapies

Therapeutic agents are usually designed against basic cellular processes, so the proteins encoded by the core genome are specific and promising candidates as drug targets

Copper serves as the functional engine of the peptide, driving enzymatic reactions that influence everything from collagen synthesis to vascular development

15,89,90 The second category involves synaptic proteins, including cell adhesion, scaffolding, and signalling molecules, which can affect synapse structure and function during different processes of synapse formation, elimination, transmission, and plasticity

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