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doi:10.1186/s12933-014-0129-4

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Although free radicals participate in physiological shedding, their overproduction can cause unintended tissue injury

After APAP administration, liver injury was detected in both KO and WT mice

In some studies, healthy participants help researchers learn more about: How the body processes medications How medical devices function during testing Baseline biological data that supports future research Early safety information for new therapies These insights help guide the development of future treatments and improve the overall understanding of human health