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Diagnosis With a history of fava bean ingestion or of administration of a potentially hemolytic drug (see Table 18-3 ) followed by hemoglobinuria (see Table 18-4 ), the diagnosis is almost always straightforward, and it can be made quite confidently even before obtaining the final proof that the patient is deficient in G6PD (discussed later in this chapter)

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Muscle weakness, joint pain, and chronic fatigue are also reported, as oxidative stress affects energy production in cells

doi: 10.1111/j.1600-6143.2007.01829.x

Investigations assess cytokine-expression profiles, epithelial-barrier integrity, mucosal architecture, tight-junction organization, and tissue-remodeling responses following experimental enteral delivery