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In 2 retrospective studies of ketamine for the treatment of refractory headache, which included individuals with chronic migraine, continuous subanesthetic doses of intravenous ketamine reduced headache severity acutely when dosed from 0.1 mg/kg/h to a maximum of 1 mg/kg/h titration based on drug tolerability

10.1016/j.jdermsci.2015.09.003 232 XinL.GaoJ.LinH.QuY.ShangC.WangY.et al (2020)

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221 Compared to subcutaneous fat, visceral fat exhibits a significantly greater capacity to secrete pro-inflammatory cytokines and chemokines