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Linking microcircuit dysfunction to cognitive impairment: effects of disinhibition associated with schizophrenia in a cortical working memory model

doi :10.1016/0891-5849(94)90029-9

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Dose Community protocols range from 2-5 mg/kg

Although istradefylline was associated with a significantly higher risk of dyskinesia compared to placebo (RR = 1.72, 95% CI = 1.26 to 2.34, p = 0.0007), no significant differences were observed for mild adverse reactions such as tremor, nausea, constipation, hallucinations, insomnia, somnolence, or accidents