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As I elaborate on in my video The Symptoms of Vitamin B12 Deficiency , these include: Abdominal distention Chronic diarrhea Shortness of breath Swollen, red, painful feet Skin darkening Bilateral useless hand syndrome Numbness and tingling in the hands and feet Muscle cramps Dizziness Cognitive disturbances Difficulty walking Erectile dysfunction Fatigue Depression Psychosis Coma Blindness Vitamin B12 Deficiency Treatment Is A Vitamin B12 Shot Better Than Taking B12 Orally

That number's not nearly as large today

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The NHS and NICE recommend PDE5 inhibitors (sildenafil, tadalafil, vardenafil, avanafil) as first-line treatment, alongside lifestyle modifications and management of underlying conditions

Singh et al., 2020