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NAD + is an electron carrier in glycolysis and the Krebs cycle, where it is converted into the reduced form NADH, which is essential for ATP production (127, 128)

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In part, the increase in oxidative stress is attributable to mitochondrial dysfunction in OA chondrocytes 88,89

Given the function of post acetabular glands in producing mucous like substances to facilitate attachment to host skin, it is possible that these cysteine proteases may have a role in overcoming the skin as an immune barrier

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