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*Correspondence: Gang Hou, [email protected] This article was submitted to Experimental Pharmacology and Drug Discovery, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Month 1: initial assessment Run a basic metabolic panel and fasting glucose at 4 weeks, just before your first dose escalation from 2.5 mg to 5 mg

Note that fixed costs are known in total, but Amy does not allocate fixed costs to each department