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O., Osaki, K

Glutathione is the most abundant antioxidant made in the human body and acts as a critical regulator of oxidative stress

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Among all the special regulations that exist for rare diseases, the most important for SCA3 are 1) the possibility of orphan drug status [241], 2) the financial breaks on approved drugs and devices [242], and 3) the possibility of combining trial phases [237]

In conclusion, these data show that an important reason underlying elevated oxidative stress in type 2 diabetes is deficiency of glutathione, which occurs because of the decreased synthesis caused by limited availability of the precursor amino acids cysteine and glycine