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The derivative of synthetic heroin, 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), elicits PD-like symptoms in experimental primates and rodents and drug addicts, giving a clear clue that environmental factors may be involved in the development of this disease (Quik et al., 2006a,b)

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NCCVF is For a point process, NACVF and NCCVF represent strength of correlation as a function of time on a monotonic scale ranging from 1 to +1 31

Biological studies indicate possible dangers of vaping, including pulmonary toxicity and lung cancer