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It has been shown that the mTOR pathway is involved in the regulation of neurogenesis, synaptic plasticity, neuronal development and excitability (LaSarge and Danzer 2014)

Nicotinamide is a precursor of NAD+, the central cofactor of energy metabolism

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In contrast, the link between oxidative stress and herpesvirus infection was much weaker in captive animals

Dihexa's synaptogenic effects require activation of the c-Met receptor, as demonstrated by experiments using c-Met-specific short hairpin RNA (shRNA) which completely abolished Dihexa's capacity to induce spine formation