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Phillyrin has also been shown to reduce glycocalyx shedding by inhibiting LPS-induced cathepsin L and ROS production

Moreover, alcoholics may experience reduced intestinal absorption of vitamin B 12 (2), and individuals with acquired immunodeficiency syndrome (AIDS) appear to be at increased risk of deficiency, possibly related to a failure of the IF-B 12 receptor to take up the IF-B 12 complex (3)