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The symptoms of a vitamin B-12 deficiency may include: Fatigue, weakness Memory loss Depression Confusion Insomnia Shortness of breath Poor sense of balance Vision problems Diarrhoea or constipation Loss of appetite Cognitive functioning problems Beefy, red, smooth and sore tongue Sore mouth and/or bleeding gums Numbness and tingling of hands and feet Loss of hearing and tinnitus Pale, possibly yellowish pallor in light-skinned individuals

Influences stressrelated pathways that affect neuroendocrine balance

In people whose vitamin B 12 deficiency is related to overgrowth of intestinal bacteria, treatment with oral antibiotics such as tetracycline (sold under several brand names) may stop bacterial overgrowth and allow the absorption of vitamin B 12 to return to normal

Through the VEGFR2-Akt-eNOS pathway, it promotes angiogenesis (new blood vessels), ensuring that the metabolically active fibroblasts stimulated by GHK-Cu receive the oxygen and nutrients needed for protein synthesis

The compound has attracted attention from researchers working at the intersection of aging biology and skin regeneration