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A portion of this work was supported by NASA funds to the Jet Propulsion Laboratory, to the California Institute of Technology, and to the Southwest Research Institute
In addition, antagonists of corticotropin-releasing factor 1 (CRF 1) have some antidepressant and anti-anxiety effects [69, 70], via mechanisms possibly related to the involvement of CRF 1 in the hypothalamic-pituitary-adrenal (HPA) axis [58]
A new SIRT1 inhibitor, MHY2245, induces autophagy and inhibits energy metabolism via PKM2/mTOR pathway in human ovarian cancer cells
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