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To uphold the BBB's integrity and support healthy neuronal metabolism, a continuous and sufficient blood supply is essential for the proper functioning of the brain

135 ZIP9 and ZIP10 play essential roles in B cell receptor signaling pathways, influencing B cell activation 136,137 (Fig

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coli L-asparaginase involved the addition of polyethylene glycol group into the native enzyme that can reduce immunogenicity and prolonged half-life (1.24 day for native and 5.73 days for pegylated formulation) [100]

The development of the nervous system in progeny may be influenced epigenetically by molecules associated with one-carbon metabolism, such as betaine, choline, and folate (Ars et al., 2019)