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Conversely, increasing the Bacteroidetes to Firmicutes ratio through high intake of dietary fiber may reduce caloric extraction from the diet and support weight loss (76)

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[email protected] These authors have contributed equally to this work This article was submitted to Antimicrobials, Resistance and Chemotherapy, a section of the journal Frontiers in Microbiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Concurrently, the E3 ligase ZNRF2 tunes the ubiquitination of the auxiliary subunit SLC3A2 at K147, driving its plasma membrane translocation to maximize cystine import in lung adenocarcinoma, which can be therapeutically blocked by the synthetic peptide K147 [36]