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Divergent transcriptional regulation of astrocyte reactivity across disorders

Based on the fitted pKa of 6.87, which is in good agreement with the average of 6.52 from other reported values (11, 5759), the amount of niclosamide in aqueous solution increases in the higher pH range (of 8-9.5)

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This dietary intervention trial received ethical approval from the Quadram Institute Bioscience Human Research Governance Committee (QIB01/2024) and the South East Scotland Research Ethics Committee (24/SS/0047) and is registered at ClinicalTrials.gov (NCT06518343)

doi: 10.1039/C9LC00496C 162 GoyalGPrabhalaPMahajanGBauskBGilboaTXieLet al