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Orthostatic hypotensiona 20 mmHg drop in systolic pressure when standingoften accompanies this condition and increases fall risk, especially in adults over 65

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Individual biochemistry, receptor sensitivity, and unknown factors mean some people simply don't respond to GHK-Cu as expected

Therefore, with carbidopa around, the enzyme that converts levodopa into dopamine does not work as well and less levodopa is converted into dopamine in the bloodstream and more makes it into the brain

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