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These baseline labs help your medical team identify any underlying conditions, evaluate your current metabolic function, and determine whether tirzepatide is the safest and most effective option for your specific situation

But it has not been ruled out, and the FDA's briefing documents noted it as an uncharacterized risk requiring further investigation before any approval

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[5] report elevated NET markers in serum and follicular fluid of women with PCOS, these findings are constrained by small sample sizes (57 PCOS patients and 38 controls), limiting statistical power to detect robust correlations with metabolic or hormonal indices such as testosterone and HOMA-IR