Benhamed F, Denechaud PD, Lemoine M, Robichon C, Moldes M, Bertrand-Michel J, Ratziu V, Serfaty L, Housset C, Capeau J, Girard J, Guillou H, Postic C (2012) The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans
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Often called the bodys master antioxidant, it plays an important role in: Cellular health: helping to protect cells from free radical damage Detoxification: supporting liver function and toxin removal Immune function: regulating immune system responses and reducing inflammation Oxidative stress reduction: neutralising harmful reactive oxygen species Glutathione is made from three amino acids, which makes it a tripeptide
Defining context-specific vulnerabilities within this network may provide a unifying framework for ferroptosis-based therapeutic strategies in cancer