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Hepatic drug metabolizing enzyme induction and implications for preclinical and clinical risk assessment

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Peer review Peer review information Nature Metabolism thanks Timothy Wai and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

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Fasting was likewise required for CR-mediated molecular changes, including CR-induced reduction in brain mTOR signaling and the activation of autophagy

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The participants provided written informed consent before entering the study

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