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3 Nicotine pharmacology and cardiovascular effects 3.1 Mechanisms of nicotine action As detailed by Benowitz (22) in his comprehensive review of nicotine pharmacology, nicotines addictive potential stems from its complex interaction with the nervous system, involving rapid central nervous system penetration and subsequent activation of neural reward pathways

Marijuana use can negatively impact an individual's life in the following ways: It may seem like marijuana's side effects dissipate after use, but it can also cause long-term side effects