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Intellia and Regeneron made history in June 2021 with NTLA-2001 when they announced positive early data from the first-ever patients to have their DNA edited with an in vivo CRISPR/Cas9 therapy delivered systemically

The excitation and emission monochromators were set at 1 mm, giving a spectral bandwidth of 4.25 nm

The selective ULK1/2 inhibitor, DCC-3116, synergizes with the KRASG12C inhibitor sotorasib to suppress KRAS-driven LC, whereas this combination has been assessed only in early preclinical stages and lacks predictive biomarkers for patient stratification (17)

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10.1016/j.bbi.2024.04.022 101 WheelerM