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As a result, when we were offered the opportunity to continue for the next five years, we decided to turn down the offer and let a new organization pick up the work

The effectiveness of the TJs results from the strong linkage of trans membranal claudins and occludins to intracellular actin and the cytoskeleton induced by cytoplasmic scaffolding proteins, zonula occludentes (ZO-1, 2, and 3) (Pandit et al., 2020)

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