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An approximately 30% reduction in the rate of cognitive decline observed in individuals treated with these agents is considered clinically meaningful, as it reflects sustained cognitive function and a delay in progression to the more advanced stages of AD

Glutamine oxidation maintains the TCA cycle and cell survival during impaired mitochondrial pyruvate transport

Choosing the best combination of spectral filters for each biochemical parameter independently using PLS When the filter combination optimization was performed for each parameter individually, it was not possible to define a recurrent spectral filters combination for smoothing, baseline correction, normalization, and others (Table 2)

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Animals with sustained blood glucose of 200 after 5days were considered as being diabetic [11]