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Hi Arlene, Youd need to consult with a functional medicine specialist because each case is individual and may depend on multiple factors

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The sufferer may be asymptomatic as long as his medicine is taken regularly

Single-cell RNA-seq reveals transcriptomic heterogeneity and post-traumatic osteoarthritis-associated early molecular changes in mouse articular chondrocytes

Its also worth noting that excess selenium can lead to increased oxidative stress rather than relieve it, so consume no more than 400 micrograms of selenium per day