Evidence Against the Gateway Hypothesis The strongest evidence challenging gateway drug theory as a universal mechanism includes: The National Institute of Justice (2018), after reviewing 23 peer-reviewed studies, concluded no causal link between cannabis use and other illicit drug use can be established, noting that statistical correlation persists across populations but direct pharmacological causation cannot be claimed from observational data alone
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Additional chlorpyrifos concerns include various environmental impacts, like groundwater contamination and toxicity to birds, bees, and aquatic organisms
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