It is studied as a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme linked to metabolic and oncogenic pathways in research models
PubMed Sikiric, P., Separovic, J., Anic, T., Buljat, G., Mikus, D., Seiwerth, S., Grabarevic, Z., Stancic-Rokotov, D., Pigac, B., Hanzevacki, M., Marovic, A., Rucman, R., Petek, M., Ziger, T., Sebecic, B., Zoricic, I., Turkovic, B., Aralica, G., Perovic, D., Duplancic, B., Lovric-Bencic, M., & Rotkvic, I
Yue X, Liu SL, Guo JN, Meng TG, Zhang XR, Li HX, Song CY, Wang ZB, Schatten H, Sun QY, Guo XP
Heres whats most commonly at play: Genetics: Androgenetic alopecia stems from sensitivity to DHT, a hormone that miniaturizes follicles over time
When introduced to the body, BPC-157 will activate the ERK1/2 signaling pathway and indicate to the body that it should form new blood vessels, which helps bring essential nutrients and oxygen to damaged tissue