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Sulforaphane suppresses PRMT5/MEP50 function in epidermal squamous cell carcinoma leading to reduced tumor formation

The primary outcomes were the percentage weight change and the proportion of participants losing at least 5% of their baseline weight, using treatment-policy estimand analysis (intention-to-treat principle)

PTMs are critical molecular events in a series of biological processes such as cell growth, proliferation, differentiation, metabolism, and apoptosis ( Protein oxidation Cysteine residues in proteins are easily oxidized by ROS, reactive nitrogen species, reactive sulfur species, or GSH