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For animals, B12 oral supplements are not ideal, as it would require taking large quantities for the right amount to be absorbed

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[58] Medical uses [edit] Treatment of deficiency [edit] Severe vitamin B 12 deficiency is initially corrected with daily intramuscular injections of 1000 g of the vitamin, followed by maintenance via monthly injections of the same amount or daily oral dosing of 1000 g

Individuals at higher risk include older adults with reduced stomach acid production, people with gastrointestinal conditions affecting absorption, strict vegans, and those taking medications like metformin or proton pump inhibitors