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Non-specific expression in normal hepatocytes causes hepatotoxicity, which can be mitigated by introducing an AFP promoter for HCC-specific expression

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Emerging evidence suggests that molecules such as PTEN-induced putative kinase 1 (PINK1), parkin RBR E3 ubiquitin protein ligase (PRKN), dynamin-related protein 1 (DRP1), and peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1-), as well as the signaling pathways they affect, play an important role in respiratory-related diseases

Among smokers and ex-smokers, we recognized a considerable number of cases of unclassifiable IIP with peculiar pathological changes that cannot be explained by the ATS/ERS classification