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Moreover, GABA induced marked enhancement whereas bicuculline (GABA-A receptor antagonist) led to significant inhibition of influx (GABA vs

866 This suggests a model, not yet tested, in which the -NAC peptide and the N-terminal tail of ZNG1 are in competition with one another and given increased cellular expression of ZNG1 under conditions of Zn II limitation, 56 may help to ensure that inactive metal-free METAP1 does not readily associate with the ribosome