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Under these observations, the EC and CH were sorted as potential inhibitors for the melanin production in the murine melanoma cells, and hence, can be considerded for further hyperpigmentation treatment

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thaliana mutant lines used in our study were ordered from the European Arabidopsis Stock Centre (NASC) or kindly donated by authors (see Supplementary Table S1 for further details)

Patients exhibiting clinical or hematologic response consistent with polycythemia vera should be referred for further evaluation

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