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In this case, the percent sequence length identity was maintained from the CLC-based analysis for the single-end reads, except for the paleofecal sample, where the % identity was lowered to 98% to obtain full coverage
Given that cyanide exposure from linamarin is strongly associated with the development of konzo, an increase in plasma oxidative stress may also affect cyanide action or metabolism, potentially amplifying its capacity to induce mitochondrial stress or giving rise to its oxidized form cyanate, which is a strong neurotoxin in various experimental models that can further decrease glutathione levels in the CNS 52,53
10.1021/mp800206b 19 BrufaniM.RizziN.MedaC.FilocamoL.CeccacciF.DAiutoV.et al (2017)
Discard any pen or vial left outside the recommended range for extended periods and request a replacement