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In chemotherapy-sensitive patients, Keap1 (Kelch-like ECH-associated protein 1) binds to NRF2 and mediates NRF2 ubiquitination via the Cul3-E3 ligase complex, promoting its degradation and maintaining NRF2 at low levels [32]

This tripeptide structure is the basis for all biological activities of glutathione

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NAD+ to NADH conversion cycle But NAD+ does more than just energy production

A cross-sectional study in 2023 reported that 17.7% of the patients with vitiligo had one or more autoimmune comorbidities (Rios-Duarte et al., 2023)