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For kinetic CYP3A4 activation and inhibition testing, ketoconazole or rifampicin (MilliporeSigma, catalog: R7382) was prepared at 2 final concentration in culture medium containing 2 luminogenic CYP substrate

Wu et al., 2020)

OS arises when an imbalance between free-radical formation and antioxidant defenses occurs, that is, when ROS concentration overwhelms the antioxidant capacity within the RBC [19]