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448 The NAD + biosynthesis regulated by NAMPT in adipocytes plays an important role in the pathogenesis of obesity-related metabolic complications

Increased adiposity leads to a higher burden of senescent cells, 35 amplifying local and systemic inflammation through the secretion of pro-inflammatory cytokines and other bioactive molecules

As a result, experiments can be planned around a known molar mass and a known sequence, and results are easier to compare between laboratories

Studies on the role of further protein kinases in eryptosis are solely based on cell culture experiments and pharmacological evidence: Activation of serine/threonine-protein kinase C (PKC) induces eryptosis (Fig