and the interplay between the endoplasmic reticulum and actin to drive the contraction of the Drp1 protein to reduce the molecular spacing, leading to the rupture of the OMM and IMM and ultimately triggering mitochondrial fission (Giacomello et al., 2020
Despite promising preclinical data, clinical trials in humans are extremely limited, and the compound remains largely experimental, with ongoing research required to fully characterize pharmacokinetics, optimal dosing, long-term safety, and potential off-target effects
The risk is likely lower for patients who are already at or near their goal weight and switching for maintenance purposes, but nutritional vigilance remains essential
Available in 10/10mg and 30/30mg stable lyophilized vials
You can put a band-aid or bandage on the site if it bleeds