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(C, D) RAW264.7 cells were infected with AdV-empty vector or AdV-Grx for 2 days (MOI 10) before stimulation with HSV-2 (310 6 pfu/ml, MOI 3) or ODN1826 (1 M) as indicated

First, astrocytes protect neurones in the penumbra, and second, after the end of infarct expansion, astrocytes form a peri-infarct barrier very similar to the perilesional barrier in the TBI