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In hippocampal tissues, mRNA expression studies at 1 h and 24 h, and strongly elevated ( Egr1, Akt1, Kras, Src, Foxo, Srf, Vegfr2, Nos3, Nos1 ) and decreased ( Nos2, Nfkb ) gene expression ( Mapk1 not activated) also support BPC 157 beneficial effect on brain lesions, given in reperfusion in stroke-rats [30]

Baba S, Iwasa M, Higashi K, Minatoguchi S, Yamada Y, Kanamori H, Kawasaki M, Nishigaki K, Minatoguchi S (2017) Antidiabetic drug alogliptin protects the heart against ischemia-reperfusion injury through GLP-1 receptor-dependent and receptor-independent pathways involving nitric oxide production in rabbits

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