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IQOS ILUMA generates no cigarette smell and produces less smell than cigarettes.* *93% agreement amongst 674 adult consumers in Japan and Italy, 2020 - 2021 While both are smoke-free alternatives to cigarettes, heated tobacco and vaping are not the same

The reasons for this are unclear but involve: Vascoconstriction and lack of oxygen reaching skin cells Delayed migration of keratinocytes Decreased collagen synthesis Delayed growth of new blood vessels within the wound

23 September 2000

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Headache is likely a result from dehydration (CIR, 2014)