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For example, unlike bacterial or protozoal infections, which require 100% cure rates or risk relapse, reduction of worm burdens by 50% would lead to significant decreases in pathology and morbidity associated with schistosomiasis, and no rebound in pathology would occur because adult worms do not multiply in their host

Even though alternative models are available, such as animal models or ex vivo models, in vitro models offer higher experimental flexibility and reproducibility, making them a valuable tool for the understanding of pathophysiological mechanisms of several diseases, such as CVDs

Accumulation of cytosolic dsDNA contributes to fibroblast-like synoviocytes-mediated rheumatoid arthritis synovial inflammation

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